It Starts with the Egg

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Rebecca Fett is the author of "It Starts with the Egg," a book that explores evidence-based strategies for improving fertility and increasing the chances of a successful pregnancy. Fett herself struggled with infertility and underwent multiple rounds of in vitro fertilization (IVF) before ultimately conceiving.

If you’re trying to conceive, timing intercourse during your fertile window is crucial, but it’s not the whole story—egg quality plays an equally vital role. High-quality eggs are genetically stable, reducing the risk of chromosomal abnormalities, which account for 41% of miscarriages. While egg quantity is fixed, quality can be influenced by supporting mitochondrial function, which powers egg maturation. Protecting eggs from toxins like BPA, found in plastics, and adopting a nutrient-rich diet with slow-release carbs, lean proteins, and folate can further enhance fertility. Supplements like CoQ10, which boosts mitochondrial efficiency, and antioxidants like melatonin or vitamin C, can also improve egg quality, particularly for IVF. A healthy diet and prenatal vitamins are a good starting point, with additional supplements tailored to individual needs under medical guidance. Up next, we’ll explore actionable steps to optimize your fertility journey.

“If you are trying to conceive through IUI or IVF, you will benefit most if CoQ10, alpha-lipoic acid, N-acetylcysteine, vitamin E, and DHEA are started at least two to three months before your egg retrieval or insemination, if possible. For melatonin, the recent successful studies have started the supplement one month or two weeks before egg retrieval.”

“The real concern now is that manufacturers are simply replacing BPA with very closely related chemicals, such as bisphenol S and bisphenol F. At a practical level, this means it is much better to minimize canned food and replace plastic with glass and stainless steel, rather than simply buying products labeled as BPA free. This is important because new research indicates that BPA’s cousins can compromise fertility in exactly the same way.”

“Chemicals in commercial lubricants Research has recently revealed yet another group of chemicals that can interfere with fertility: those found in lubricants. Studies show that most lubricant brands significantly decrease sperm motility and increase DNA fragmentation."

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